Blended Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant use of opioids with other opioid analgesics, including butorphanol, nalbuphine, pentazocine, may well lessen the analgesic effect of oxycodone and acetaminophen tablets and/or precipitate withdrawal symptoms. Advise patient to prevent concomitant use of such drugs.La o